Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
| Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
| Upregulated in class | DMpreB |
| GeneSet | HUMANCYC_SUPERPATHWAY OF HISTIDINE, PURINE, AND PYRIMIDINE BIOSYNTHESIS |
| Enrichment Score (ES) | 0.8182928 |
| Normalized Enrichment Score (NES) | 1.5740603 |
| Nominal p-value | 0.003690037 |
| FDR q-value | 0.03170977 |
| FWER p-Value | 0.488 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CTPS | 2514 15772 | 86 | 2.716 | 0.0670 | Yes | ||
| 2 | GART | 22543 1754 | 107 | 2.575 | 0.1339 | Yes | ||
| 3 | ATIC | 14231 3968 | 108 | 2.568 | 0.2017 | Yes | ||
| 4 | NME4 | 23065 1577 | 120 | 2.545 | 0.2682 | Yes | ||
| 5 | NME2 | 9468 | 150 | 2.439 | 0.3310 | Yes | ||
| 6 | IMPDH2 | 10730 | 254 | 1.927 | 0.3763 | Yes | ||
| 7 | NME1 | 9467 | 273 | 1.870 | 0.4247 | Yes | ||
| 8 | PPAT | 6081 | 274 | 1.868 | 0.4740 | Yes | ||
| 9 | RRM2 | 5401 5400 | 303 | 1.762 | 0.5189 | Yes | ||
| 10 | CAD | 16886 | 321 | 1.716 | 0.5633 | Yes | ||
| 11 | GUK1 | 20432 | 335 | 1.679 | 0.6069 | Yes | ||
| 12 | ADSL | 4358 | 398 | 1.551 | 0.6445 | Yes | ||
| 13 | NME6 | 3139 19297 | 523 | 1.347 | 0.6733 | Yes | ||
| 14 | PAICS | 16820 | 542 | 1.323 | 0.7073 | Yes | ||
| 15 | RRM1 | 18163 | 718 | 1.089 | 0.7266 | Yes | ||
| 16 | GMPS | 15578 | 748 | 1.059 | 0.7530 | Yes | ||
| 17 | DHODH | 7152 | 801 | 1.020 | 0.7771 | Yes | ||
| 18 | PRPS1 | 24233 | 878 | 0.937 | 0.7978 | Yes | ||
| 19 | UMPS | 22606 1760 | 1006 | 0.838 | 0.8130 | Yes | ||
| 20 | IMPDH1 | 17197 1131 | 1244 | 0.683 | 0.8183 | Yes | ||
| 21 | PRPSAP1 | 20141 | 2370 | 0.245 | 0.7642 | No | ||
| 22 | AK3L1 | 8564 | 3435 | 0.066 | 0.7087 | No | ||
| 23 | AK5 | 6042 | 4325 | 0.032 | 0.6617 | No | ||
| 24 | KIF13B | 21982 21983 | 4743 | 0.024 | 0.6399 | No | ||
| 25 | NME7 | 926 4101 14070 3986 3946 931 | 5926 | 0.013 | 0.5767 | No | ||
| 26 | RRM2B | 6902 6903 11801 | 6266 | 0.011 | 0.5587 | No | ||
| 27 | AK1 | 4363 | 8517 | 0.003 | 0.4377 | No | ||
| 28 | PURA | 9670 | 10425 | -0.001 | 0.3351 | No | ||
| 29 | PRPSAP2 | 10013 1317 | 12945 | -0.010 | 0.1998 | No | ||
| 30 | CTPS2 | 12060 2571 | 17449 | -0.671 | -0.0247 | No | ||
| 31 | AK2 | 8563 2479 16073 | 17531 | -0.720 | -0.0101 | No | ||
| 32 | ADSSL1 | 21136 2087 | 18112 | -1.256 | -0.0082 | No | ||
| 33 | NME3 | 23349 | 18167 | -1.336 | 0.0242 | No |
